10-Day Europe Trip From Amsterdam: Italy and Switzerland
Browse more guides: Switzerland travel | Europe destinations 10-Day Europe Trip From Amsterdam: Italy and Switzerland Last updated: April 2026 · 12 min read I've made multiple Amsterdam, Switzerland, and Italy combo trips, and the 10-day version is the one I keep recommending to friends who want both Alps and ancient cities without dying of train fatigue. Ten days. Five cities. One flight, three trains, zero regrets if you pick the right cities. Here's the route I keep coming back to: Amsterdam 2 nights → Interlaken 3 nights → Milan or Lake Como 1 night → Florence 2 nights → Rome 2 nights, fly home from Rome FCO. It works because Switzerland sits roughly between the Netherlands and Italy, so you're not backtracking. Trains do most of the heavy lifting. One quick budget flight at the start saves you a full travel day. TL;DR: Route Amsterdam (2N) → Interlaken (3N) → Milan/Como (1N) → Florence (2N) → Rome (2N). Train and one flight intra-Europe. Daily mid-range budget...